Industrial Pharmacy I - for B. PHARMACY PCI SYLLABUS - 17 ( SEM V- BP502T) - TEXTBOOK

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UNIT - I Preformulation Studies : Introduction to preformulation, goals and objectives, study of physicochemical characteristics of drug substances. a.Physical properties : Physical form (crystal and amorphous), particle size, shape, flow properties, solubility profile (pKa, pH, partition coefficient), polymorphism b.Chemical properties : Hydrolysis, oxidation, reduction, racemisation, polymerization BCS classification of drugs and its significant Application of preformulation considerations in the development of solid, liquid oral and parenteral dosage forms and its impact on stability of dosage forms. (Chapter - 1) UNIT - II Tablets : a.Introduction, ideal characteristics of tablets, classification of tablets. Excipients, Formulation of tablets, granulation methods, compression and processing problems. Equipments and tablet tooling. b.Tablet coating : Types of coating, coating materials, formulation of coating composition, methods of coating, equipment employed and defects in coating. c.Quality control tests : In process and finished product tests. (Chapter - 2) Liquid orals : Formulation and manufacturing consideration of syrups and elixirs suspensions and emulsions; Filling and packaging; evaluation of liquid orals official in pharmacopoeia. (Chapter - 3) UNIT - III Capsules : a.Hard gelatin capsules : Introduction, Production of hard gelatin capsule shells. size of capsules, filling, finishing and special techniques of formulation of hard gelatin capsules, manufacturing defects. In process and final product quality control tests for capsules. UNIT - IV Parenteral Products UNIT - V Cosmetics

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Author: [Dr. Suhas S. Sidheshwar, Dr. Smitha gandra, Dr. Ramdas T. Dolas, Dr. Meera Singh, Dr. Abhijeet D. kulkarni] Pages: 324 Edition: 2021 Vendors: Technical Publications