Pharmaceutical Organic Chemistry I for B. PHARMACY PCI SYLLABUS - 17 ( SEM II - BP202T) - TEXTBOOK

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UNIT-I Classification, nomenclature and isomerism Classification of Organic Compounds Common and IUPAC systems of nomenclature of organic compounds (up to 10 Carbons open chain and carbocyclic compounds) Structural isomerisms in organic compounds (Chapters - 1, 2) UNIT-II Alkanes*, Alkenes* and Conjugated dienes* sp3 hybridization in alkanes, Halogenation of alkanes, uses of paraffins. Stabilities of alkenes, sp2 hybridization in alkenes E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs orientation and evidences. E1 verses E2 reactions, Factors affecting E1 and E2 reactions. Ozonolysis, electrophilic addition reactions of alkenes, Markownikoff’s orientation, free radical addition reactions of alkenes, Anti Markownikoff’s orientation. Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical addition reactions of conjugated dienes, allylic rearrangement (Chapters - 3, 4, 5) UNIT-III Alkyl halides* SN1 and SN2 reactions - kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations. SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions Structure and uses of ethylchloride, chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform. Alcohols* - Qualitative tests, Structure and uses of Ethyl alcohol, Methyl alcohol, chlorobutanol, Cetosteryl alcohol, Benzyl alcohol, Glycerol, Propylene glycol (Chapters - 6, 7) UNIT-IV Carbonyl compounds* (Aldehydes and ketones) Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation, Perkin condensation, qualitative tests, Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin, Cinnamaldehyde. (Chapter - 8) UNIT-V Carboxylic acids* Acidity of carboxylic acids, effect of substituents on acidity, ind

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Author: [Dr. Sachin K. Bhosale, Dr. Shreenivas R. Deshpande, Dr. Nirmala V.Shinde] Pages: 370 Edition: 2022 Vendors: Technical Publications