Pharmaceutical Inorganic Chemistry for B. PHARMACY PCI SYLLABUS - 17 ( SEM I - BP104T) TCA PHARMA

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Introduction to pharmaceutical inorganic chemistry: Different Pharmacopoeia and contents of individual monographs. Indian Pharmacopoeia – History and detail study of different volumes along with general notices, new inclusion/exclusion of compound monograph, Pharmaceutical Aids. (Chapter - 1) 2. Sources of contamination in pharmaceuticals and methods to control: Source of impurities, Purity test, Various limit tests including chloride, sulphate, arsenic, lead, iron and heavy metals as per IP, Qualitative tests for alkali and alkaline earth metals. (Chapter - 2) 3. Water: Physical properties of water, Water as universal pharmaceutical vehicle, Hardness of water, methods to remove hardness of water, Different official waters and official control tests for water. (Chapter - 3) 4. Gastrointestinal agents: Acidifying agents: Dilute hydrochloric acid, Antacids: Classification of antacids, Aluminium hydroxide gel, Aluminium phosphate, Basic Aluminium carbonate, Calcium carbonate, Magnesium carbonate, Magnesium hydroxide, Magnesium trisilicate, Sodium bicarbonate, Combination of Antacids, Protectives and adsorbents: bismuth compounds, Bismuth subcarbonate, Kaolin, Activated charcoal, Pectin, Saline cathartics: Sodium orthophosphate, Sodium potassium tartarate, Magnesium carbonate, Kaolin, Bentonite, Magnesium sulphate. (Chapter - 4) 5. Electrolytes: Extra and intracellular ions: Chlorides, Phosphate, Bicarbonate, Na, K, Ca, Mg, Electrolytes used for replacement therapy, Calculation of mEq/l, mOsmol/l of electrolytes, Physiological acid base balance. Electrolyte used in acid-base therapy, Electrolytes combination therapy. Sodium chloride injection, Ringer solution lactated, Ringer injections, Sodium acetate, Potassium bicarbonate, Sodium citrate, Calcium gluconate, Sodium lactate, Ammonium chloride, Oral rehydration salts. (Chapter - 5) 6. Essential and trace elements: Absorption, distribution, physiological role: Official compound of Fe: Ferrous sulfate, Iron sorbitex injection, Ferric ammonium citrate, Ferric chloride, Ferrous gluconate. Cu: Copper sulfate, Iodine, Potassium iodide, Sodium iodide, Zn-Zinc sulphate. (Chapter - 6) 7. Topical agents: General introduction and mode of action Protectives: Talc, Zinc oxide, Calamine, Zinc stearate, Titanium dioxide, Aluminum compounds, Antimicrobials and astringents: Hydrogen peroxide solution, Sodium perborate, Zinc peroxide, Potassium permanganate, Sodium hypochlorite, Iodine and its preparation, Solution, Boric acid, Selenium sulfide, Chlorinated lime, Zinc sulfate. (Chapter - 7) 8. Dental products: Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement. (Chapter - 8) 9. Inorganic gases and vapours: Important inorganic gases used in Pharmacy Oxygen, Nitrogen, Nitrous oxide, Carbon dioxide, Helium, Ammonia and their compounds as per I.P. (Chapter - 9) 10. Expectorants: Ammonium chloride, Potassium iodide. (Chapter - 10) Part - II 11. Radioopaque medium: Barium sulphate. (Chapter - 11) 12. Antidotes: Sodium nitrite, Sodium thiosulphate, Activated charcoal. (Chapter - 12) 13. Antidepressant: Lithium carbonate. (Chapter - 13) 14. Cytotoxic agents: Cisplatin (Chapter - 14) 15. Emetics: Copper sulphate, Sodium potassium tartarate. (Chapter - 15) 16. Radiopharmaceuticals: Radio activity, Measurement of radioactivity, Properties of α, β, γ radiations, Half-life, radio isotopes and study of radio isotopes: Sodium iodide 131I, Storage conditions, precautions and pharmaceutical application of radioactive substances. (Chapter - 16) 17. Haematinics: Ferrous sulphate, Ferrous gluconate. (Chapter - 17) 18. Chemical measurements: Methods of expressing concentration of solutions, Preparation of general reagents (As per IP), SI Units and Prefixes, Derived SI Units with Special Names, SI Prefixes, Safety Symbol. (Chapter - 18) 19. Salt analysis: Introduction to analytical chemistry, Detection of cations and anions. (Chapter - 19) 20. Acids, Bases and Buffers: Acid - base theories, Acid - base equilibrium in water, the pH scale, distribution of acid - base species with pH, weak acids and bases, salts of weak acids and bases, buffers, polyprotic acids and their salts. Acid base titration curves for strong acid-strong base titration, weak acid - strong base titration, weak base - strong acid titration, titration of polyfunctional acids and bases, acid - base indicators, titration of amino acid. (Chapter - 20)

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Author: [Dr. Vitthal Chopade, Dr. Padmanabh Deshpande, Shital Patil] Pages: 136 Edition: 2022 Vendors: Technical Publications