Syllabus Pharmacology • General Pharmacology : Introduction and scope of Pharmacology, Various routes of drug administration - advantages and disadvantages, Drug absorption - definition, types, factors affecting drug absorption, Bioavailability and the factors affecting bioavailability, Drug distribution - definition, factors affecting drug distribution, Biotransformation of drugs - Definition, types of biotransformation reactions, factors influencing drug metabolisms, Excretion of drugs - Definition, routes of drug excretion, General mechanisms of drug action and factors modifying drug action. (Chapter - 1) • Drugs Acting on the Peripheral Nervous System : Steps involved in neurohumoral transmission, Definition, classification, pharmacological actions, dose, indications, and contraindications of : a) Cholinergic drugs b) Anti-Cholinergic drugs c) Adrenergic drugs d) Anti-adrenergic drugs e) Neuromuscular blocking agents f) Drugs used in Myasthenia gravis g) Local anaesthetic agents h) Non-Steroidal Anti-Inflammatory drugs (NSAIDs) (Chapter 2) • Drugs Acting on the Eye : Definition, classification, pharmacological actions, dose, indications and contraindications of : Miotics, Mydriatics, Drugs used in Glaucoma. (Chapter 3) • Drugs Acting on the Central Nervous System : Definition, classification, pharmacological actions, dose, indications, and contraindications of : General anaesthetics, Hypnotics and sedatives, Anti-Convulsant drugs, Anti-anxiety drugs, Anti-depressant drugs, Anti-psychotics, Nootropic agents, Centrally acting muscle relaxants, Opioid analgesics. (Chapter 4) • Drugs Acting on the Cardiovascular System : Definition, classification, pharmacological actions, dose, indications, and contraindications of : Anti-hypertensive drugs, Anti-anginal drugs, Anti-arrhythmic drugs, Drugs used in atherosclerosis and Congestive heart failure, Drug therapy for shock. (Chapter 5) • Drugs Acting on Blood and Blood Forming Organs : Definition, classification, pharmacological actions, dose, indications, and contraindications of : Hematinic agents, Anti-coagulants, Anti-platelet agents, Thrombolytic drugs. (Chapter 6) • Definition, classification, pharmacological actions, dose, indications, and contraindications of : Bronchodilators, Expectorants, Anti-tussive agents, Mucolytic agents. (Chapter 7) • Drugs Acting on the Gastro Intestinal Tract : Definition, classification, pharmacological actions, dose, indications, and contraindications of : Anti-ulcer drugs, Anti-emetics, Laxatives and purgatives, Anti-diarrheal drugs. (Chapter 8) • Drugs Acting on the Kidney : Definition, classification, pharmacological actions, dose, indications, and contraindications of : Diuretics, Anti-Diuretics. (Chapter 9) • Hormones and Hormone Antagonists : Physiological and pathological role and clinical uses of : Thyroid hormones, Anti-thyroid drugs, Parathormone, Calcitonin, Vitamin D, Insulin, Oral hypoglycemic agents, Estrogen, Progesterone, Oxytocin, Corticosteroids. (Chapter 10) • Autocoids : Physiological role of Histamine, 5 HT and Prostaglandins, Classification, clinical uses, and adverse effects of antihistamines and 5 HT antagonists. (Chapter 11) • Chemotherapeutic Agents : Introduction, basic principles of chemotherapy of infections, infestations and neoplastic diseases, Classification, dose, indication and contraindications of drugs belonging to following classes : Penicillins, Cephalosporins, Aminoglycosides, Fluoroquinolones, Macrolides, Tetracyclines, Sulphonamides, Anti-tubercular drugs, Anti-fungal drugs, Anti-viral drugs, Anti-amoebic agents, Anthelmintics, Anti-malarial agents, Anti-neoplastic agents. (Chapter 12) • Biologicals : Definition, types, and indications of biological agents with examples. (Chapter 13)
