Unit - I : Molecular Structure and Theories of Bonding Atomic and Molecular orbitals. Linear Combination of Atomic Orbitals (LCAO), molecular orbitals of diatomic molecules, molecular orbital energy level diagrams of , and molecules. molecular orbitals of butadiene and benzene. Crystal Field Theory (CFT): Salient Features of CFT - Crystal Field Splitting of transition metal ion d-orbitals in Tetrahedral, Octahedral and square planar geometries. Band structure of solids and effect of doping on conductance. (Chapter - 1) Unit - II : Water and its Treatment Introduction - hardness of water - Causes of hardness - Types of hardness: temporary and permanent - expression and units of hardness - Estimation of hardness of water by complexometric method. Potable water and its specifications. Steps involved in treatment of water - Disinfection of water by chlorination and ozonization. Boiler feed water and its treatment - Calgon conditioning, Phosphate conditioning and Colloidal conditioning. External treatment of water - Ion exchange process. Desalination of water - Reverse osmosis. Numerical problems. (Chapter - 2) Unit - III : Electrochemistry and Corrosion Electrochemical cells - electrode potential, standard electrode potential, types of electrodes - calomel, Quinhydrone and glass electrode. Nernst equation, Determination of pH of a solution by using quinhydrone and glass electrode. Unit - IV : Stereochemistry, Reaction Mechanism and Synthesis of Drug Molecules Introduction to representation of 3-dimensional structures, Structural and stereoisomers, configurations, symmetry and chirality. Enantiomers, diastereomers, optical activity and Absolute configuration. Unit - V : Spectroscopic Techniques and Applications Principles of spectroscopy, selection rules and applications of electronic spectroscopy. vibrational and rotational spectroscopy. Basic concepts of Nuclear magnetic resonance Spectroscopy, chemical shift. Introduction to Magnetic resonance imaging. (Chapter - 5)
