{"product_id":"9789390770861-2","title":"Pharmacology I for  B. PHARMACY  PCI  SYLLABUS - 17  ( SEM IV - BP404T) - TEXTBOOK","description":"\u003cp\u003eUNIT-I  1. General Pharmacology a.\tIntroduction to Pharmacology- Definition, historical landmarks and scope of pharmacology, nature and source of drugs, essential drugs concept and routes of drug administration, Agonists, antagonists( competitive and non competitive), spare receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, allergy. b.\tPharmacokinetics- Membrane transport, absorption, distribution, metabolism and excretion of drugs. Enzyme induction, enzyme inhibition, kinetics of elimination (Chapter - 1) UNIT-II General Pharmacology a.\tPharmacodynamics- Principles and mechanisms of drug action. Receptor theories and classification of receptors, regulation of receptors. drug receptors interactions signal transduction mechanisms, G-protein–coupled receptors, ion channel receptor, transmembrane enzyme linked receptors, transmembrane JAK-STAT binding receptor and receptors that regulate transcription factors, dose response relationship, therapeutic index, combined effects of drugs and factors modifying drug action. b.\tAdverse drug reactions. c.\tDrug interactions (pharmacokinetic and pharmacodynamic) d.\tDrug discovery and clinical evaluation of new drugs -Drug discovery phase, preclinical evaluation phase, clinical trial phase, phases of clinical trials and pharmacovigilance. (Chapters - 2,3,4,5,6,7,8)   UNIT-III 2. Pharmacology of drugs acting on peripheral nervous system a.\tOrganization and function of ANS. b.\tNeurohumoral transmission,co-transmission and classification of neurotransmitters. c.\tParasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics. d.\tNeuromuscular blocking agents and skeletal muscle relaxants (peripheral). e.\tLocal anesthetic agents. f.\tDrugs used in myasthenia gravis and glaucoma (Chapter - 9) UNIT-IV 3. Pharmacology of drugs acting on central nervous system a.\tNeurohumoral transmission in the C.N.S.special emphasis on importance of various neurotransmitters like with GABA, Glutamate, Glycine, serotonin, dopamine. b.\tGeneral anesthetics and pre-anesthetics. c.\tSedatives, hypnotics and centrally acting muscle relaxants. d.\tAnti-epileptics e.\tAlcohols and disulfiram (Chapters - 10,11,12,13,14) UNIT-V 3. Pharmacology of drugs acting on central nervous system a.\tPsychopharmacological agents : Antipsychotics, antidepressants, anti-anxiety agents, anti-manics and hallucinogens. b.\tDrugs used in Parkinsons disease and Alzheimer’s disease. c.\tCNS stimulants and nootropics. d.\tOpioid analgesics and antagonists e.\tDrug addiction, drug abuse, tolerance and dependence. (Chapters - 15,16,17,18)\u003c\/p\u003e","brand":"Technical Publications","offers":[{"title":"Default Title","offer_id":46828242501803,"sku":"11959541612","price":605.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0620\/3355\/9723\/files\/9789390770861_1_d0eef5a8-0a6a-4b1b-8790-60417295ca6a.jpg?v=1778239053","url":"https:\/\/technicalpublications.in\/products\/9789390770861-2","provider":"Technical Publications","version":"1.0","type":"link"}